Panadol Extra is considered ideal for those seeking the benefits of Panadol, in addition to a greater analgesic effect against mild and moderate pains such as headache, toothache, and menstrual pain, the ingredients in Panadol provide a stronger pain-relieving effect by up to 37% compared to regular paracetamol, and it is gentle on the stomach when used according to the instructions. Panadol Extra is a paracetamol-based pain reliever that reduces fever and severe pains such as headache, including migraine, muscle pain, menstrual pain, ear pain, and sore throat. How to use For oral use only. Adults including the elderly and children aged 12 years and above: take 2 tablets up to 4 times a day, 8 tablets in 24 hours. Do not exceed the specified dose. It should not be used with other products containing paracetamol. Not recommended for children under 12 years. Warnings and precautions: Always read the label, use the treatment as directed only, for relief of pain and fever, improper use can be harmful. This treatment should not be taken at the same time as other products containing paracetamol. Do not take this treatment if you are allergic to paracetamol or any other ingredients in this product. If symptoms persist, consult a doctor or pharmacist. If you have any liver or kidney problems, consult a doctor before taking Panadol. Please see a doctor if symptoms do not improve. If symptoms continue, worsen, or new symptoms appear, consult a doctor as these may indicate a serious condition. If you have glutathione deficiency conditions such as sepsis, consult a doctor before taking Panadol. Avoid drinking too many caffeinated beverages, such as coffee or tea, when taking this medication. Keep this medication out of sight and reach of children. Overdose of paracetamol: Immediate medical care is needed in case of overdose to avoid the risk of liver failure, even if no symptoms of overdose appear. An overdose of more than 10 grams of paracetamol can cause liver failure. Early signs may include pallor, nausea, vomiting, diaphoresis, and general discomfort. Clinical and laboratory evidence of liver damage may not be apparent until 48 to 72 hours after the overdose. The overdose should be treated immediately by gastric lavage and then administering acetylcysteine or methionine intravenously without waiting for plasma paracetamol levels. Supportive measures should also be available. The importance of additional treatment is also studied in light of plasma paracetamol levels and the time elapsed since ingestion. Caffeine overdose: An overdose of caffeine may lead to epigastric pain, vomiting, diuresis, irregular heartbeat or arrhythmia, central nervous system stimulation, insomnia, discomfort, agitation, tremors, shivering, and seizures. It is noteworthy that for clinically significant symptoms of caffeine overdose associated with this product, the amount consumed will be linked to a serious case of paracetamol-related liver toxicity. There is no specific treatment for this, but supportive measures can be used. In all cases suspected of overdose, immediate medical care is critical for adults and children, even if no signs or symptoms are observed. Daily long-term use of paracetamol with warfarin and other coumarins used as blood thinners may increase the risk of bleeding; consult your doctor before taking these medications together. Incidental doses of paracetamol have little effect. Alcohol use can increase the hepatotoxic effects of Panadol Extra. Panadol Extra is not recommended during pregnancy due to the potential increased risk of miscarriage associated with caffeine consumption. This product should not be used during breastfeeding without medical consultation. Caffeine in breast milk may have a stimulant effect on infants, but no significant toxicity is observed.